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Cosmic runes are used for a variety of purposes, including enchanting jewellery and crossbow bolts, and are always in high demand. Each cosmic rune is worth only about the same as one pure essence, so making a single cosmic from one ess is not a moneymaker. At level 59 Runecrafting, though, you can make double cosmics, and that changes the money situation quite a bit!
And the November 2009 Runecrafting update means you now get more runes per essence between multiple rune milestones, which greatly increases cosmic rune profitability between levels 27 and 59. This makes cosmic crafting profitable at mid levels.
There are many different approaches for runecrafting cosmic runes. Some players just walk back and forth between the bank and altar, but that's very slow. Using the Abyss is always an option, but some players hate going into the Wilderness. An alternative is a method I developed that makes use of the fairy rings in conjunction with the new ring of Slaying that you can unlock using Slayer points. The main advantage of this technique is that you don't have to worry about revenant attack or getting skulled. The main benefit of the abyss method, however, is that you can craft more runes per hour and it also makes it easy to repair your Runecrafting pouches.
You should not need to use energy potions, as run energy will restore rapidly at high levels due to the June 2009 energy update.
Note that if your Agility level is marginal, you may be better off taking the single lower-level shortcut instead of the two higher-level ones.
All information based on Grand Exchange price data from: May 20, 2012. Note that the three-day delay in price updates is waived for RuneScoop members.
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