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The fastest way to get to the main location is to use a ring of slaying, if you've unlocked the ability to use them. Otherwise, use the fairy rings to go to code "A J R". In either case, the cave entrance is just to the east of where you arrive, and the cave crawlers are in the first room. When needed, use slayer rings and duelling rings to bank, or the fairy ring network to bank in Zanaris.
If you want to fight in the lumbridge swamp caves, the shortcut opened up as part of the Lost Tribe quest is preferred; they are in a couple of chambers in the central part of the dungeon.
You can fight these in Dorgesh-Kaan South Dungeon, but the only convenient way of getting there is by fairy ring (code "A J Q") -- so you might as well fight them in their primary spot, which is more convenient.
Equipment
Standard melee gear is sufficient for these. There are safe spots for rangers or mages, though meleeing is much faster.
To fight in the alternate locations you will need a covered light source.
Supplies
These monsters poison only on contact, and they rarely hit high-level players who are properly equipped. Thus, you can just bring regular antipoisons and use a dose as needed. Mid-level and lower-level players will get hit more frequently, and so will want to use super antipoisons, which give immunity for six minutes per dose. They will also need food, where high-levels do not.
Super attack and super strength potions are recommended, as always, to increase kill speed.
Familiar
These monsters drop tons of herbs and are easy to access with a ring of slaying, so I strongly recommend using a macaw to improve herb drop value rather than a beast of burden.
Combat Notes
These monsters die quickly and shouldn't be a problem for even mid-level players. Safe-spotting is easy enough, but still bring antipoisons just in case. Just don't mess around with their poison (like thinking you can ride it out for a few minutes to finish a Slayer assignment.) Despite being only level 23, their poison hits starting at about 80 and can kill you quickly if you don't have an antipoison.
Drop Notes
In addition to their plentiful herb drops, these monsters are somewhat of a "one-stop Herblore shop" in that they also drop vials of water and some useful secondary ingredients. You can save inventory space (and even make another antipoison if needed) by combining the herbs, vials of water and secondary ingredients that these monsters drop in large quantities. Cave crawlers also provide seeds and runes, though the runes are usually too small in number to warrant spending an inventory slot on.
These monsters can drop multiple items at once, such as seeds, an herb and a charm.
They also drop bronze boots, which are surprisingly valuable -- be sure to keep them!